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Emphysema

Lung Disease

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Facts

Emphysema is a chronic lung condition in which the lungs’ natural airspaces, called alveoli, become larger but decrease in number. The tissue surrounding the alveoli loses elasticity so that the airspaces can no longer expand and shrink as usual. This reduces the amount of oxygen transferred by the lungs to the bloodstream. Air gets trapped in these spaces rather than exhaled, making it more difficult for you to breathe. Emphysema can be part of a lung disease called chronic obstructive pulmonary disease or COPD.

Emphysema is a chronic lung disorder where alveoli enlarge and lose elasticity, reducing oxygen transfer. Often caused by smoking and pollutants, it makes breathing difficult and is part of COPD.

Emphysema usually results from exposure to toxins like cigarettes as well as air pollution, dust, chemical fumes, and irritants. Older adults are more likely to be affected and many people who have emphysema are not aware that they have it. The damage of emphysema cannot be reversed, but treatment may help slow the progression of the disease.

Causes

Cigarette smoking is the number one cause of emphysema. Although smoking has decreased in Canada for many years, it’s still a major concern. A huge majority of emphysema sufferers are current smokers or have smoked in the past. Smoking is responsible for 80% to 90% of chronic obstructive pulmonary disease (COPD) cases, including emphysema. Smoking is also responsible for the majority of all lung cancer cases in Canada. A burning cigarette emits over 7,000 different chemicals, many of which are carcinogenic (cancer-causing) or otherwise toxic to living tissue. Being exposed to secondhand smoke also increases your risk of developing emphysema.

Infections of the respiratory tract can also destroy lung tissue and thus contribute to the development or worsening of emphysema. Likewise, having emphysema increases the likelihood of infection.

Heredity is occasionally a factor in emphysema. Carriers of a specific genetic abnormality called homozygous alpha-1-antitrypsin deficiency are at high risk of developing emphysema. However, it is relatively rare and accounts for less than 1% of cases. If you have alpha-1-antitrypsin deficiency, it’s vital not to smoke.

Aging naturally brings changes to the lungs and air sacs even in non-smokers. The loss of elasticity can eventually become severe enough to be classified as emphysema. Air pollution can also irritate the lungs and cause emphysema, although pollution alone is rarely the cause.

Treatment and Prevention

The first treatment for emphysema is to stop smoking. Your lungs won’t repair themselves, but at least further damage can be slowed.
Treatments include:

  • Bronchodilators such as beta-agonists and anticholinergic medications, which help to relax and open the airways.
  • Corticosteroids that reduce inflammation may be used, and these may prevent flare-ups that require hospitalization.
  • Antibiotics when there is evidence of infection.
  • Exercise can help strengthen muscles so that less demand is placed on the lungs with activity.
  • Lung surgery, or a lung transplant, can be lifesaving in the small number of people who are candidates for it. In a surgery called lung volume reduction, the most diseased part of the lung (20% to 30%) is removed. This allows the remaining lung and muscles to work better, improving breathing. Research is ongoing to determine if the same benefit can be achieved by removing the emphysematous lung tissue non-surgically (i.e., by using valves or glue). Other research is assessing if coil springs can be inserted into the lungs to regain elasticity.
  • Oxygen therapy, which is used to increase the percentage of oxygen that the body receives on each breath. Machines that concentrate oxygen may be used in the home.
  • Purified human alpha-1-antitrypsin for treatment of emphysema due to alpha-1-antitrypsin deficiency.
  • Vaccinations against COVID-19, influenza, and pneumonia, as recommended by your doctor to help avoid respiratory infections. This doesn’t treat the emphysema but can prevent flare-ups.

For the vast majority of people with emphysema, the best way to prevent it and slow it down is to not smoke. This outweighs all other considerations.
Following these tips can help protect your lungs if you have emphysema:

  • Avoid secondhand smoke.
  • Avoid air pollution as much as possible.
  • Exercise when possible
  • Use air conditioning with a filter and humidity control.
  • Avoid allergic "triggers" that can aggravate emphysema if asthma coexists.
  • Avoid cold air, which can cause the lungs to spasm
  • Avoid high altitudes.
  • Wash your hands and brush your teeth frequently to avoid infections.

All material copyright MediResource Inc. 1996 – 2025. Terms and conditions of use. The contents herein are for informational purposes only. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Source: www.medbroadcast.com/condition/getcondition/Emphysema

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