Condition Lookup

Benign Prostatic Hyperplasia

BPH, Prostate Problems

Facts

The prostate gland is a small, round lump of tissue located between the penis and the bladder. Its function is to add fluid to the semen, the liquid that carries the sperm. It tends to grow bigger as men enter middle age, and continues to grow with age. In some men the prostate gland can grow to be more than seven times its original size. This runaway growth is called hyperplasia and results in the condition benign prostatic hyperplasia (BPH).

BPH causes no symptoms or problems in a quarter of men by the age of 55, and in half of men by the age of 75, where the chance of developing symptoms increases with each additional year. The prostate surrounds the top of the urethra, the tube through which we urinate, just where it meets the bladder. If the prostate gets too big, it can squeeze the urethra, partly closing it. This can lead to various urinary tract problems.

Having BPH doesn’t increase your chances of getting prostate cancer. The two diseases can have similar symptoms, although prostate cancer often has no symptoms. It’s also possible to have BPH and prostate cancer at the same time.

Causes

We don’t know why the prostate grows larger in older men, but it’s believed to be linked to hormonal changes associated with aging.

Treatment and Prevention

Your doctor may recommend watchful waiting, especially if the symptoms are mild and do not interfere with your daily life. Watchful waiting involves monitoring for signs of worsening symptoms without any treatment.

Medications called alpha-blockers (e.g., terazosin*, alfuzosin, tamsulosin, silodosin) can help relax the bladder outlet, allowing easier passage of urine, especially if the obstruction of the urethra isn’t too severe. Other medications (e.g., dutasteride, finasteride) help reduce the size of the prostate.

These medications can remove the need for surgery in many people with BPH. However, surgery is the only way to eliminate the problem completely. The most commonly used technique is called a TURP (transurethral resection of the prostate), which can be used for most cases except those with extremely large prostate glands. A tube equipped with a camera and a loop is inserted into the urethra (the tube that runs the length of the penis and back to the bladder) to remove strips of enlarged prostate. TURP causes fewer postoperative problems than open surgery, which involves an abdominal incision and the risk of blood transfusion.

Other techniques like TUIP (transurethral incision of the prostate), laser prostatectomy, and plasma vaporization aim to reduce the size of the prostate, often with fewer side effects than TURP. Only a specialist can decide which technique is most appropriate in each case.

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