Before you begin using a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use this medication.
Abnormal heart rhythms: Certain medications used to treat abnormal heart rhythms, including disopyramide, can also cause new abnormal heart rhythms, some of which can be life-threatening. Treatment with disopyramide should be started in the hospital, where appropriate monitoring and treatment can be provided.
Glaucoma: Disopyramide may cause an increase in the pressure inside the eye and should not be used by people with glaucoma. If you have a family history of glaucoma, your doctor will monitor you closely while taking this medication.
Heart failure: Disopryamide can cause or worsen heart failure and should not be used by people with severe or untreated heart failure. If you have heart failure and are taking this medication, your doctor will monitor you closely during treatment. If you notice shortness of breath; weight gain; or swelling in the hands, feet, or lower legs while taking disopyramide, contact your doctor immediately.
Kidney or liver disease: People with reduced kidney or liver function may need a lower dose of disopyramide. Your doctor will monitor your closely while you are taking this medication. People with severely reduced kidney or liver function should not take this medication.
Low blood pressure: This medication may cause low blood pressure. If you experience dizziness, lightheadedness, or fainting while taking this medication, contact your doctor immediately.
Low blood sugar: Disopyramide can cause low blood sugar, especially for people with certain medical conditions (e.g., heart failure, treated diabetes, chronic malnutrition, liver disease, kidney disease) or who are taking certain medications (e.g., atenolol, propranolol, metoprolol). If you are at risk of experiencing low blood sugar while taking this medication, your doctor will monitor your blood sugar closely during treatment.
Myasthenia gravis: Disopyramide may make this condition worse. Talk to your doctor about whether any special monitoring is needed.
Reduced concentration: This medication may reduce the ability to concentrate and react. Do not drive or operate machinery until you know how this medication affects you.
Urine retention problems: Disopyramide may cause urine retention. If you experience any difficulties with urination while taking this medication, contact your doctor.
Pregnancy: This medication should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant while taking this medication, contact your doctor immediately.
Breast-feeding: This medication passes into breast milk. If this medication is essential, you should not breast-feed while taking it.
Children: The safety and effectiveness of using this medication have not been established for children.