Before you begin using a medication, be sure to inform your doctor of any medical conditions or allergies you may have, any medications you are taking, whether you are pregnant or breast-feeding, and any other significant facts about your health. These factors may affect how you should use this medication.
Drowsiness/reduced alertness: This medication may cause faintness or dizziness. Do not drive, operate machinery, or perform other potentially hazardous tasks until you have determined how this medication affects you.
Heart disease: Isosorbide-5-mononitrate may cause some symptoms of heart disease to become worse. If you have heart problems caused by not enough oxygen being available for the heart or other organs of the body, discuss with your doctor how this medication
may affect your medical condition, how your medical condition may affect the dosing and effectiveness of this medication, and whether any special monitoring is needed.
Low blood pressure: Symptoms of severe lowering of blood pressure, such as weakness or dizziness, particularly when rising suddenly from a sitting or lying position, may occur. People who are prone to low blood pressure (e.g., those taking diuretics) should be cautious when using this medication.
Tolerance: With continued use, isosorbide-5-mononitrate may stop having beneficial effects because the body gets used to it (i.e., develops a tolerance). Call your doctor if at any time you feel that your angina attacks are getting worse or happening more often.
Withdrawal: Stopping this medication suddenly may occasionally aggravate chest pain or other symptoms of angina. To avoid possible withdrawal effects, this medication should be gradually reduced and not stopped suddenly. Do not change the way you
are taking this medication without speaking to your doctor.
Pregnancy: Studies demonstrating the safety and effectiveness of using isosorbide-5-mononitrate during pregnancy are not available. This medication should not be used during pregnancy unless the benefits outweigh the risks. If you become pregnant
while taking this medication, contact your doctor immediately.
Breast-feeding: It is not known if isosorbide-5-mononitrate passes into breast milk. If you are a breast-feeding mother and are taking this medication, it may affect your baby. Talk to your doctor about whether you should continue breast-feeding.
Children: The safety and effectiveness of using this medication have not been established for children. Its use by this age group is not recommended.
Seniors: Seniors may be more likely to experience dizziness or lightheadedness while taking this medication.